Printer-friendly versionTo fully realize the promise of personalized medicine, clinicians and life sciences researchers need access to clinical (or biomedical) information, including data contained in medical records or in clinical trials records; and to molecular information, including genomics, proteomics, and other molecular and cellular data. The seamless integration of these two data types for analysis embodies the concept of translational research.
GenoLogics provides database applications and data repositories that integrate clinical and biomolecular raw and processed data, supporting centralized data management and marshalling to statistical and bioinformatics analysis systems.
Integrated Translational Data Repository: Benefits and Capabilities
• Supports the integration of clinical and research data in one system
• Web interface for research teams to annotate and upload datasets to data repository, allowing data to be easily uploaded and integrated into a secure Cloud storage system accessible to all project stakeholders
• Provides query interface for quickly finding and accessing data sets, downloading them for data analysis
• Data repository for the raw and processed data files – hosted on Amazon S3
• Data repository supports URI (uniform resource identifier) generation – to facilitate data access and web downloads
• Delivers low cost data storage provided by Amazon
• Database with structured data model and support for flexible annotations:
o Structured data model supports: studies, patients/participants, samples
o Annotations engine using the Entity–Attribute–Value (EAV) paradigm, allows diverse clinical and biomolecular data to be imported into the database for querying
o Seamless method for analysts and data manager to adapt the data model and annotations to enable new and diverse data fields for querying
o Data model will support URIs to point to raw and processed data sets for download
• Web portal with query interface for investigators to search, find, and download data sets
